New Leicester signing Youri Tielemans could make his debut, with Foxes boss Claude Puel set to make a late decision on the Monaco loanee.
Puel has reported no new fitness concerns ahead of the weekend.
Manchester United are hopeful Paul Pogba and Anthony Martial will overcome minor injuries to be available for Sunday’s game.
The fit-again Chris Smalling could make his first appearance for two months, but Marcos Rojo remains sidelined.
Leicester confirm loan signing of Tielemans
Martial signs new Man Utd contract
Leicester have won just one of their last 21 league and cup games against Manchester United (D4, L16).
That solitary victory was by 5-3 at home in September 2014, when the Foxes came back from 2-0 and 3-1 down.
Leicester have won just four Premier League home games this season – only three sides have lower tallies: Southampton, Crystal Palace and Huddersfield.
The Foxes could lose three consecutive home league matches for the first time since 2014.
Leicester have earned 13 points from losing positions this season, more than any other Premier League side prior to the latest round of fixtures.
They have won just one of their last 14 matches on a Sunday in all competitions (D4, L9), which came against Everton in Claude Puel’s first game in October 2017.
United are vying to win five consecutive away games in all competitions for the first time since a similar streak in September and October 2012, in Sir Alex Ferguson’s final season in charge.
They are the only team to have received a yellow card in all 24 of their Premier League matches this season.
Juan Mata has scored four goals and assisted two more in his last five league appearances against Leicester, netting in each of his last two games at the King Power Stadium (three goals in total).
Paul Pogba has been involved in 53% of the 19 league goals scored by United under Ole Gunnar Solskjaer. He has scored six times (including two penalties) and registered four assists.
Marcus Rashford is likely to make his 100th Premier League appearance on Sunday. At 21 years and 95 days old, he would become the youngest player to reach a century of top-flight appearances for United since Ryan Giggs in December 1993.